| Competences |
| Type A | Code | Competences Specific |
| Common | ||
| AC2 | To integrate knowledge of main metabolic pathways and nutrients in situations of health and illness. | |
| Professional | ||
| Research | ||
| Type B | Code | Competences Transversal |
| Common | ||
| BC4 | Autonomy, responsibility and initiative | |
| Type C | Code | Competences Nuclear |
| Common | ||
| CC2 | To be advanced users of the information and communication technologies | |
| Learning aims |
| Objectives | Competences | ||
| To integrate the knowledge of the main metabolic pathways and the role of nutrients in situations of health and disease. | AC2 |
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| To work autonomously with initiative. | BC4 |
||
| To use specific tools of ICTs for professional development derived from the postgraduate course. | CC2 |
||
| Contents |
| Topic | Sub-topic |
| Topic 1. Introduction to Molecular Nutrition | Concept of molecular nutrition against the “classic” concept of nutrition. Gene regulation and nutrient-gene interactions. Regulation types for nutrients. Research methods in molecular nutrition: application of genomic and post-genomic technologies. Trends of molecular nutrition: nutrigenomics and nutrigenetics. |
| Topic 4. Role of nutrients on gene expression | Gene regulation by carbohydrates. Gene regulation by fats: fatty acids, cholesterol. Gene regulation by amino acids: growth inhibition by protein malnutrition. Gene regulation by vitamins: vitamin A. |
| Topic 5. Diet and genetic polymorphisms. | Genetic differences in the perception of taste. Sensitivity to bitter taste |
| Topic 6. Nutrition and epigenetics. | Diet and DNA methylation. Niacin status, poly(ADP-ribose) metabolism and genomic instability. Diet and miRNAs. |
| Topic 5. Nutrigenomics and longevity | Processes associated with aging. Theory of aging based on ROS of mitochondrial origin. Effect of caloric restriction and protein restriction on longevity. |
| Topic 6. Microbiota | Microbiota and its immunomodulatory action at intestinal level |
| Planning |
| Methodologies :: Tests | |||||||||
| Competences | (*) Class hours | Hours outside the classroom | (**) Total hours | ||||||
| Introductory activities |
|
2 | 1 | 3 | |||||
| Lecture |
|
23 | 23 | 46 | |||||
| Assignments |
|
6 | 18 | 24 | |||||
| Personal attention |
|
2 | 1 | 3 | |||||
| (*) On e-learning, hours of virtual attendance of the teacher. (**) The information in the planning table is for guidance only and does not take into account the heterogeneity of the students. | |||||||||
| Methodologies |
| Description | |
| Introductory activities | To transmit the objectives pursued, detailing the contents that will be worked. To explain the methodology used for the subject. To communicate and make clear evaluation criteria |
| Lecture | Exposition of course contents through presentations by specialists of the subjects. |
| Assignments | To write a title and an abstract of a scientific article, related to molecular nutrition and provided by the teacher. |
| Personal attention | To answer questions out of the classroom. |
| Personalized attention |
|
|
| Assessment |
| Description | Weight | ||
| Assignments | Write a title and an abstract of a scientific article, related to molecular nutrition and provided by the teacher. | 100% | |
| Other comments and second exam session | |||
|
The subject has only one call. During the exams, all devices that aren't authorized for the test must be switched off and stored. Performing a fraudulent activity during an exam, including material, virtual or electronic support will lead to the failing of the test. With independence of this, taking into account the gravity of the facts, the centre will propose the initiation of disciplinary expedient which will be initiated according to the resolution of the chancellor. |
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| Sources of information |
| Basic |
R. Brigelius-Flohé i H-G. Joost, Nutritional Genomics: Impact on Health and Disease, WILEY-VCH, 2006
N. Moustaid-Moussa i C. D. Berdanier, Nutrient-gene interactions in health and disease, CRC Press, 2001
J. Zempleni i H. Daniel, Molecular Nutrition, CABI, 2003
J. Kaput i R. L. Rodriguez, Nutritional Genomics: Discovering the Path to Personalized Nutrition, WILEY-INTERSCIENCE, 2006 |
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| Complementary | |||||||||
| Recommendations |
(*)The teaching guide is the document in which the URV publishes the information about all its courses. It is a public document and cannot be modified. Only in exceptional cases can it be revised by the competent agent or duly revised so that it is in line with current legislation.