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Type A
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Code |
Competences Specific |
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Common |
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Professional |
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Research |
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Type B
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Code |
Competences Transversal |
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Common |
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Type C
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Code |
Competences Nuclear |
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Common |
| Objectives |
Competences |
| To differentiate the molecular, cellular and tissue elements that are part of the immune system. |
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| To describe the physiological importance of different types of leukocytes. |
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| To classify the different defence mechanisms and list the elements involved. |
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| To relate the mechanisms and effects of the non-specific and specific immune responses. |
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| To explain the physiological mechanisms of mucosal response and tolerance. |
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| To describe the main pathologies associated with immune dysfunction. |
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| To learn the techniques using the antibody as a methodological tool. |
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| To search information to update and complete the study of immunology. |
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| To interpret a scientific text in the context of Immunology. |
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| To critically analyse practical exercises on the changes and processes studied. |
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| To show attitude of observation and inquiry, in addition to critical thinking and interest in continuous education. |
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| Topic |
Sub-topic |
Topic 1.- INTRODUCTION TO THE IMMUNE SYSTEM (3 h)
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History. Characteristics and properties of the immune system. Natural and acquired immunity: concept of antigen. Elements of the immune System: immunocompetent cell, molecules and lymphoid tissues. |
| Topic 2.- NATURAL OR INNATE IMMUNE RESPONSE (3 h) |
Characteristics and elements. Physical, chemical and biological natural barriers. Phagocytosis. Complement system. Natural Killer cells (NK). Inflammation and inflammatory processes. |
| Topic 3.- ACUIRED OR SPECIFIC IMMUNE RESPONSE (I) (2,5 h) |
Characteristics. Involved cells: lymphocytes and antigen-presenting cells. Antibodies: structure, isotopes, and features. Antigen receptors. Molecules of the major histocompatibility complex. |
| Topic 4.- ACUIRED OR SPECIFIC IMMUNE RESPONSE (II) (2,5 h) |
Processing and antigen presentation. Activation and differentiation of lymphocytes T CD4+: effectors and memory. Polarization Th1/Th2. Immune response mediated by T CD8+ cells: cytotoxicity. Immune response mediated by cell B: humoral response. |
Topic 5.- MUCOSAL IMMUNE SYSTEM (1 h)
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Structure of lymphoid tissue associated to the gut. Non-specific intestinal immune response. Specific immune response. IgA secretion. |
Topic 6.- TOLERANCE AND REGULATION OF THE IMMUNE RESPONSE (1 h)
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Central tolerance. Peripheral tolerance. Anergy. Regulatory T cells. |
Topic 7.- IMMUNOASSAY TECHNIQUES (2 h)
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Use of antibodies as laboratory reagents. Immunoassay techniques: ELISA, ELISPOT and associated techniques. Flow cytometry. Immunohistochemistry. Other assays. |
| Topic 8.- IMMUNOPATOLOGY (4 h) |
Leukocyte quantitative alterations and immunodeficiency. Hypersensitivity reactions and allergies. Autoimmune diseases. Immunotherapy: vaccines. Transplants. |
| Methodologies :: Tests |
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Competences |
(*) Class hours |
Hours outside the classroom |
(**) Total hours |
| Introductory activities |
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1 |
0 |
1 |
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| Lecture |
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19 |
24 |
43 |
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| Personal attention |
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1 |
0 |
1 |
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| Mixed tests |
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6 |
24 |
30 |
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(*) On e-learning, hours of virtual attendance of the teacher.
(**) The information in the planning table is for guidance only and does not take into account the heterogeneity of the students. |
Methodologies
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Description |
| Introductory activities |
Activities to make contact and to collect information from students. Course presentation. |
| Lecture |
The teaching of the subject is based on a theoretical component of knowledge acquisition that will be developed in the form of lectures. A theoretical and practical component is also done in the class (exercise and discussion sessions). The Virtual campus will be also used, as all the information, materials, exercises… of the course will be there. |
| Personal attention |
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Description |
| Francisco J. Pérez Cano
franciscoperez@ub.edu
Department of Physiology, Faculty of Pharmacia
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Description |
Weight |
| Mixed tests |
The evaluation system of the course aims to measure student’s learning in this field of knowledge and assess their ability to reason, integrate and relate. To this end, the evaluation will be ongoing and will be assessed from the results of three continuous assessments tests (CAT).
CAT1: Objective test that will take place after having completed topic 1 and 2. The note represents 20% of the final grade.
CAT2: Theoretical-practical exercise which includes the development of a theme- that will be assigned the first day of class-. The note represents 30% of the final grade.
CAT3: Last test that constitutes 50% of the final grade. This is an objective test of multiple choice questions and development of subject contents (Topic 1-8). CAT3 will be conducted according to the established test schedule.
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Other comments and second exam session |
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The subject has only one call.
During the exams, all devices that aren't authorized for the test must be switched off and stored. Performing a fraudulent activity during an exam, including material, virtual or electronic support will lead to the failing of the test. With independence of this, taking into account the gravity of the facts, the centre will propose the initiation of disciplinary expedient which will be initiated according to the resolution of the rector. |
| Basic |
Abbas AK, Lichtman AH, Inmunología celular y molecular, 5a edición. Madrid: Elsevier, 2004
Janeway A, Immunobiology, 6th edition. Londres: Masson Taylor & Francis, 2004
Famboeim L., Introducción a la Inmunología humana, 5a edición. Madrid: Médica Panamericana, 2005
Male D, Brostoff J, Roth DB, Roitt I., Inmunología, 7a edición. Madrid: Elsevier, 2007
Pérez-Cano FJ., Nodrint les nostres defenses, 1a ed. Barcelona: Publicacions UB-Omnis Cellula, 2010
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| Complementary |
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(*)The teaching guide is the document in which the URV publishes the information about all its courses. It is a public document and cannot be modified. Only in exceptional cases can it be revised by the competent agent or duly revised so that it is in line with current legislation. |
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