IDENTIFYING DATA 2019_20
Subject (*) STRUCTURE AND FUNCTION OF BIOMOLECULES Code 19204107
Study programme
Bachelor's Degree in Biotechnology (2009)
Cycle 1st
Descriptors Credits Type Year Period
6 Compulsory Second 1Q
Language
Català
Department Biochemistry and Biotechnology
Coordinator
PUJADAS ANGUIANO, GERARD
E-mail gerard.pujadas@urv.cat
manuel.suarez@urv.cat
sandra.guaita@urv.cat
anna.hernandez@urv.cat
raul.lopez@urv.cat
Lecturers
PUJADAS ANGUIANO, GERARD
SUÁREZ RECIO, MANUEL
GUAITA ESTERUELAS, SANDRA
HERNANDEZ AGUILERA, ANNA
LÓPEZ FERNÁNDEZ, RAUL
Web http://moodle.urv.cat
General description and relevant information Subject that aims to familiarize the student with the structure of the most relevant macromolecules biologically and correlate their structure with their function.

Competences
Type A Code Competences Specific
 A4 Know and understand in an integrated manner the organisms at molecular, cellular and metabolic level.
Type B Code Competences Transversal
 CT2 Managing information and knowledge through the efficient use of IT.
 CT3 Solve problems critically, creatively and innovatively in their field.
Type C Code Competences Nuclear

Learning outcomes
Type A Code Learning outcomes
 A4 Use bioinformatic tools to correlate the structure (proteins and nucleic acids) of a biomolecule with its function.
Type B Code Learning outcomes
 CT2 Master the tools for managing their own identity and activities in a digital environment. (Be digital)
Search for and find information autonomously with criteria of reliability and relevance. (Search)
Organize information with appropriate tools (online and face-to-face) so that they can carry out their academic activities. (Organize)
Produce information with tools and formats appropriate to the communicative situation and with complete honesty. (Create)
Use IT to share and exchange information. (Share)
 CT3 Identify the situation as a problem in the field and be sufficiently motivated to face up to it. (Understanding)
Follow a systematic method to divide a problem into parts, identify the causes and apply the knowledge specific to the discipline. (Analysis)
Design a new solution by using all the resources necessary to cope with the problem. (Creativity)
Include the details of the proposed solution in a realistic model. (Innovation)
Reflect on the model proposed, find shortcomings and suggest improvements. (Evaluation)
Type C Code Learning outcomes

Contents
Topic Sub-topic
PROTEINS
Topic 1: Non-covalent interactions
Topic 2: Covalent structure of proteins
Topic 3: Methods for determining structures
Topic 4: Secondary structure of proteins
Topic 5: Supersecondary structures
Topic 6: Tertiary structure of globular proteins
Topic 7: Quaternary structure of proteins
NUCLEIC ACIDS
Topic 8: Structural components of nucleic acids
Topic 9: Secondary structure of DNA
Topic 10: Structure of the main types of RNA
Topic 11: Foundations of specific protein-DNA recognition
GLUCIDS
Topic 12: Glyobiology
LIPIDS
Topic 13: Lipidology

Planning
Methodologies  ::  Tests
  Competences (*) Class hours
Hours outside the classroom
(**) Total hours
Introductory activities
0.5 0 0.5
Lecture
A4
30 35 65
IT-based practicals in computer rooms
CT2
CT3
30 40 70
Personal attention
0.5 0 0.5
 
Short-answer objective tests
A4
6 8 14
 
(*) On e-learning, hours of virtual attendance of the teacher.
(**) The information in the planning table is for guidance only and does not take into account the heterogeneity of the students.

Methodologies
Methodologies
  Description
Introductory activities The introduction of the subject will be done during the first hour of class and will consist of a presentation of its syllabus, its contextualization in the degree (indicating those subjects with which it is more related) and presenting the methodology that will be used for his teaching.
Lecture Exhibition of the contents of the subject.
IT-based practicals in computer rooms This is a subject with a very practical approach. In order to achieve this, the practices have been designed in a way that complements the theory provided in class and facilitates the acquisition of the indispensable abilities for the structural analysis of biological macromolecules as well as the understanding of the correlation between its structure and function they perform.
Personal attention Students can consult their questions directly to the teacher going to their office (at 106) during the visit hours (see institutional website) or also sending an email from moodle.

Personalized attention
Description
Students can consult their questions directly to the teacher going to their office (at 106) during the visit hours (see institutional website) or also sending an email from moodle.

Assessment
Methodologies Competences Description Weight        
IT-based practicals in computer rooms
CT2
CT3
The evaluation of the practices will be carried out by means of

(1) the delivery of works that will be done in groups of 4/5 students and where they will have to prove that they are able to solve complex problems effectively in the biochemical / biotechnology field. The maximum mark of this part of the evaluation of the practices is 1.5 points (with respect to the maximum grade of the subject that is 10 points)

(2) the accomplishment of a UNIQUE exam that will be carried out on the same day as the exam of theory of the first call (there will be NO test of practices in the second call since the note of practices will be the one that was obtained in the exam done on the day of the first call). The maximum mark of this part of the evaluation of the practices is 3.5 points (with respect to the maximum grade of the subject that is 10 points)

IMPORTANT NOTES: (1) attendance to ALL the practices of the subject is an indispensable requirement to be able to carry out the practice exam; and (2) there will be a UNIQUE practice exam (which will coincide with the same day that the theory exam of the first call is held)
50%
Short-answer objective tests
A4
Answer to short questions related to the part of the subject treated in the lectures. 50%
Others  
 
Other comments and second exam session

In the evaluation of the second call, the note and the weight of the practice note obtained in the first call will be maintained.

During the evaluation tests, mobile phones, tablets and other devices that are not expressly authorized for the test, must be turned off and out of sight.

The demonstrable fraudulent realization of some evaluation activity of a subject both in material and virtual and electronic support entails the student's suspense note of this evaluation activity. Regardless of this, given the seriousness of the events, the center may propose the initiation of a disciplinary file, which will be opened by resolution of the rector.


Sources of information

Basic Gómez-Moreno Calera, C., and Sancho Sanz, J., Estructura de proteínas, Ariel ciencia. Ariel, Barcelona, 2003
Neidle, S., Principles of Nucleic Acid Structure, Academic Press, cop., 2007
Rhodes, G., Crystallography made crystal clear: a guide for users of macromolecular models, Academic Press, cop., San Diego, 2000
Lesk, A.M., Introduction to protein architecture: the structural biology of proteins, Oxford University Press, cop., Oxford, UK, 2001
Lesk, A.M., Introduction to protein science, Oxford University Press, cop., Oxford, UK, 2004
Petsko, G., and Ringe, D., Protein Structure and Function, New Science Press Ltd., London, UK, 2003

Complementary

Recommendations


Subjects that it is recommended to have taken before
BIOCHEMISTRY/19204008
BIOLOGY/19204005
(*)The teaching guide is the document in which the URV publishes the information about all its courses. It is a public document and cannot be modified. Only in exceptional cases can it be revised by the competent agent or duly revised so that it is in line with current legislation.