| Competences |
| Type A | Code | Competences Specific |
| A3 | Have a good knowledge of biochemistry, enzyme kinetics and mechanisms, metabolism and its regulation. | |
| A8 | Analyse appropriately data and experimental results from the fields of biotechnology with statistical techniques and be able to interpret it. | |
| Type B | Code | Competences Transversal |
| Type C | Code | Competences Nuclear |
| Learning outcomes |
| Type A | Code | Learning outcomes |
| A3 |
Integrate knowledge of thermodynamics and kinetics into the design of biotechnological processes and obtain data for this design in the laboratory and from the literature. Be able to interpret the data of temporary evolution of chemical systems and to extract kinetic parameters. | |
| A8 |
Knows how to apply the principles of thermodynamics to chemical and biochemical processes and to systems in equilibrium. Know how to relate the conditions of temperature, pressure and composition to the equilibrium constant. Integrate knowledge of thermodynamics and kinetics into the design of biotechnological processes and obtain data for this design in the laboratory and from the literature. | |
| Type B | Code | Learning outcomes |
| Type C | Code | Learning outcomes |
| Contents |
| Topic | Sub-topic |
| Review of thermodynamic concepts | Equations of state (EoS). Thermodynamic relations and functions. Ideal gases. Mass and energy balances. 1st, 2nd and 3rd laws. Gibbs free energy and chemical potential. |
| Transformations of matter | Changes and phase equilibrium. Pure substances. Multicomponent systems. Phase diagrams. |
| Solutions | Composition and mixing variables. Ideal solutions and diluted ideal solutions. Deviation from ideal behaviour. |
| Chemical equilibrium | Stoichiometry and extent of reaction Equilibrium conditions. Equilibrium constant. Reactions in gas phase. Reactions in liquid phase. |
| Reminder of concepts of chemical kinetics | Reaction rate: rate equation, reaction order, rate constant. Mechanisms of reaction: elementary step, simple reaction, complex reaction. Apparent constant, pseudo-order. |
| Analysis of kinetic data | Methods for estimating reaction orders. Method of integration for simple reactions. Pseudo-order reaction. Apparent constant. Experimental techniques for the determination of reaction rates. |
| Influence of temperature on the rate of reactions | Arrhenius equation. Arrhenius theory. Activated complex and frequency factor. Molecular interpretation. |
| Kinetic treatment of complex reactions | Reversible reactions. Simultaneous reactions. Series reactions. Influence of temperature over complex reactions. |
| Mechanisms of reaction | Complexity of mechanisms. Approximation of the dominant step of a reaction. Steady state approach. Examples of known mechanisms. Catalytic mechanisms. Enzymatic catalysis. |
| Planning |
| Methodologies :: Tests | ||||||||||
| Competences | (*) Class hours |
Hours outside the classroom |
(**) Total hours | |||||||
| Introductory activities |
|
2 | 0 | 2 | ||||||
| Laboratory practicals |
|
10 | 15 | 25 | ||||||
| Lecture |
|
13 | 19.5 | 32.5 | ||||||
| Problem solving, exercises |
|
8 | 19.5 | 27.5 | ||||||
| Personal attention |
|
3 | 0 | 3 | ||||||
| Short-answer objective tests |
|
4 | 6 | 10 | ||||||
| (*) On e-learning, hours of virtual attendance of the teacher. (**) The information in the planning table is for guidance only and does not take into account the heterogeneity of the students. | ||||||||||
| Methodologies |
| Description | |
| Introductory activities | Review of General Chemistry concepts related to Chemical Thermodynamics and Kinetics. |
| Laboratory practicals | Work oriented to the application of the concepts acquired during the theoretical lectures. |
| Lecture | Presentation and development of the different topics, with support of materials available at the ‘’Moodle’’ workspace. |
| Problem solving, exercises | Comment and/or resolution in the classroom of problems previously delivered to students. |
| Personal attention | Individual or group discussion of doubts from problem resolution or concept revision. |
| Personalized attention |
| Description |
|
To assess students individually, or in groups if necessary, to guide them in the acquisition of technical knowledge and social skills. The assessment will take place, preferably and as far as possible, through arranged visits within hours of attention in the respective professors' offices. Both the schedules and the mechanisms of attention to the students will be established at the beginning of the course and will be informed in the Moodle workspace as well as the ways to contact. |
| Assessment |
| Methodologies | Competences | Description | Weight | ||||
| Laboratory practicals |
|
Evaluated through the laboratory report and questions in some of the objective tests, according to the calendar. | 10 | ||||
| Short-answer objective tests |
|
Partial tests will be carried out, on dates fixed and published by the Centre. Each will be dedicated to one of the parts of the subject, that is to say, Thermodynamics and Chemical Kinetics. Both parts will have the same weight, 45% + 45%. | 90 | ||||
| Others |
| Other comments and second exam session | |||
|
It is a necessary but not sufficient condition to obtain a minimum grade of 3.5 in each partial test in order to proceed to make an average. Likewise, in the laboratory section, an absence of a maximum of 3 hours will be allowed, otherwise this part will be valued with a 0. The second call replaces the partial tests and will consist of a written test made of two parts dedicated to Thermodynamics and Chemical Kinetics, respectively. In the event that any of the partial tests has been qualified with 5 or more, the mark will be maintained and only the other part will have to be completed in a time proportional to its weight. In this second call, the necessary condition also applies. Likewise, the qualification obtained in the laboratory section will be maintained. During the evaluation tests, mobile phones, tablets and other devices, which are not expressly authorized for the test, must be turned off and out of sight. The demonstratively fraudulent performance of an evaluation activity in any subject, both in material, virtual and electronic support, leads the student to a failure grade for this evaluation activity. Regardless of this, given the seriousness of the facts, the center may propose the initiation of a disciplinary process, which will be initiated by resolution of the rector. |
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| Sources of information |
| Basic |
I. N. LEVINE, Fisicoquímica, vols I y II,, Mc Graw-Hill,
P.W. ATKINS, J. de PAULA, Physical Chemistry for the Life Sciences, Freeman,
P.W. ATKINS, J. de PAULA, The elements of Physical Chemistry, Freeman,
P.W. ATKINS, Química Física, Omega,
I. N. LEVINE, Problemas de Fisicoquímica, McGraw-Hill., |
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| Recommendations |
| Subjects that continue the syllabus | |||
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| Subjects that are recommended to be taken simultaneously | ||
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