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Type A
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Code |
Competences Specific | | | A6 |
Know how to design and apply experimental laboratory protocols in the fields of biotechnology, especially chemical, biochemical, microbiological and molecular biology, assessing their risks and safety elements. |
| | A7 |
Be able to search, obtain, analyse and interpret information from the main biological databases: genomic, transcriptomic, proteomic, metabolomics, taxonomic and other, as well as bibliographic data, and use basic bioinformatics tools. |
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Type B
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Code |
Competences Transversal |
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Type C
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Code |
Competences Nuclear |
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Type A
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Code |
Learning outcomes |
| | A6 |
Know the mechanisms involved in gene expression and its regulation, both in eukaryotes and prokaryotes.
| | | A7 |
Use bioinformatic tools to correlate the structure of a biomolecule (proteins and nucleic acids) with their function.
Describe DNA recombination and repair mechanisms and modification-restriction systems.
Describe how the information in the genome is organized.
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Type B
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Code |
Learning outcomes |
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Type C
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Code |
Learning outcomes |
| Topic |
Sub-topic |
1. Introduction
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Basic concepts of Molecular genetics: DNA organization, transmission of hereditary information, DNA replication, regulation of gene transcription.
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| 2. Recombination |
Homologous recombination and specific site recombination. Importance of the mechanisms of recombination.
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| 3. Eucariotic genome |
Organization of the information. Introns and exons. Genes, pseudogenes and gene families. |
| 4. Genome of the models of study |
General characteristics of genomes of yeast, Caenorhabditis elegans, Drosophila melanogaster, Arabidopsis thaliana, Mus musculus. |
| 5. Genes and mutants |
Identification of mutants, mutants phenotype, mutation, screening and high throughput screeneing.
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| 6. Human molecular genetics |
Human genome project, genetic maps, genetic markers, polimorfisms, dna fingerprint |
| 7. Human genetic illnesses |
Monogènic illnesses, molecular basis of cancer. gene therapy. |
| Methodologies :: Tests |
| |
Competences |
(*) Class hours
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Hours outside the classroom
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(**) Total hours |
| Introductory activities |
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1 |
1 |
2 |
| Lecture |
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14 |
14 |
28 |
| Laboratory practicals |
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30 |
30 |
60 |
| Problem solving, exercises in the classroom |
|
15 |
35 |
50 |
| Personal attention |
|
1 |
0 |
1 |
| |
| Mixed tests |
|
4 |
8 |
12 |
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(*) On e-learning, hours of virtual attendance of the teacher.
(**) The information in the planning table is for guidance only and does not take into account the heterogeneity of the students. |
Methodologies
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Description |
| Introductory activities |
Activities aimed at taking contact and collecting information from the students and presenting the subject. |
| Lecture |
Exposure of the contents of the subject. |
| Laboratory practicals |
Apply, at a practical level, the theory in a given context. Practical exercises through the different laboratories. It includes computer and laboratory practices. |
| Problem solving, exercises in the classroom |
Formulation, analysis, resolution and discussion of problems, exercises and presentations of colleagues related to the topic of the subject. |
| Personal attention |
Time that each teacher has reserved to answer and solve queries to the students. |
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Description |
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Meetings in the office 111 of the Department of Biochemistry and Biotechnology, by previous appointment by email. |
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Methodologies |
Competences
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Description |
Weight |
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|
|
|
| Laboratory practicals |
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Previous and active participation, assistance and motivation, and preparation of results report. |
30% |
| Problem solving, exercises in the classroom |
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Problem solving in the classroom, participation in peer's presentations (in the debate/questions), resolution of questionnaires in ''Moodle''. |
20% |
| Mixed tests |
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It will consist of a mixed type test, which will include all the content worked on the subject. |
50% |
| Others |
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Other comments and second exam session |
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- The attendance to the laboratory practicals is compulsory. - In order to consider all the sections, a minimum grade of 5/10 of the practicals and 5/10 of the exam will be required. -The second call consists of a mixed test where all the contents of the subject are evaluated. A minimum grade of 5/10 is required. The test has a weight of 40% of the overall grade, the rest consists on the grade obtained during the course, and having attended to practicals is also compulsory. During the evaluation tests, mobile phones, tablets and other devices that are not expressly authorized for the test, must be off and out of sight. The demonstrable fraudulent realization of some evaluation activity of a subject both in material and virtual and electronic support entails the student's suspense note of this evaluation activity. Regardless of this, given the seriousness of the events, the center may propose the initiation of a disciplinary file, which will be opened by resolution of the rector. |
| Basic |
Terry Brown, Genomas, darrera publicada, Medica Panamericana
Greg Gibson; Spencer V. Muse, A Primer of Genome Science, darrera publicada, Sinauer Associates
Peter Sudbery, Genética Molecular humana, darrera publicada, Pearson
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| Complementary |
Philip Meneely , Advanced Genetic Analysis, darrera publicada , Oxford
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(*)The teaching guide is the document in which the URV publishes the information about all its courses. It is a public document and cannot be modified. Only in exceptional cases can it be revised by the competent agent or duly revised so that it is in line with current legislation. |
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