IDENTIFYING DATA 2019_20
Subject (*) CLINICAL IMMUNOLOGY Code 19204207
Study programme
Bachelor's Degree in Biotechnology (2009)
 Cycle 1st
Descriptors Credits Type Year Period
3 Optional 1Q
Language
Català
Department Basic Medical Sciences
Coordinator
CAPILLA LUQUE, JAVIER
 E-mail javier.capilla@urv.cat
frederic-francesc.gomez@urv.cat
Lecturers
CAPILLA LUQUE, JAVIER
GOMEZ BERTOMEU, FREDERIC-FRANCESC
Web
General description and relevant information La immunologia és un àrea completament vinculada a la Salut per la seva funció primària de defensa davant antígens exògens. Malgrat la seva gran plasticitat i capacitat de donar lloc a respostes altament específiques, existeixen un gran nombre de patologies associades a errades o sobre estimulació del sistema immunitari. Durant el curs es desenvoluparà una visió del sistema immunitari durant l'estat de "malaltia", els mecanismes que hi participen i com es poden manipular en favor de la salut. Una part del curs estarà orientada cap al desenvolupament d'eines immunològiques per al tractament i diagnòstic de diferents malalties.

Competences
Type A Code Competences Specific
 A6 Know how to design and apply experimental laboratory protocols in the fields of biotechnology, especially chemical, biochemical, microbiological and molecular biology, assessing their risks and safety elements.
 A7 Be able to search, obtain, analyse and interpret information from the main biological databases: genomic, transcriptomic, proteomic, metabolomics, taxonomic and other, as well as bibliographic data, and use basic bioinformatics tools.
Type B Code Competences Transversal
Type C Code Competences Nuclear

Learning outcomes
Type A Code Learning outcomes
 A6 Design a methodological flow of work that allows to obtain answers to a problem posed by the professor.
Know the advantages, limitations and disadvantages of immunological therapy.
Design fundamental strategies to solve an immune problem.
 A7 Recognize the health consequences of immune defects.
Design strategies based on solving an immune problem.
Type B Code Learning outcomes
Type C Code Learning outcomes

Contents
Topic Sub-topic
Topic 1. Immunity against infections The immune system against bacteria, viruses, fungi and parasites. Innate and adaptive response. Protective immunity and immunological memory.
Topic 2. Immunity and cancer Tumor antigens. Escape to immunosurveillance. Anti-tumor effector mechanisms. Immunotherapy and vaccines against cancer.
Topic 4. Immunodeficiencies Congenital or primary immunodeficiencies. Defects in the maturation and activation of lymphocytes. Acquired or secondary immunodeficiencies. HIV Radiation therapy and chemotherapy. Metastasis.
Topic 5. Autoimmunity and transplants Gene susceptibility to autoimmunity. Rheumatoid arthritis, diabetes mellitus, multiple sclerosis and lupus erythematosus. Gene mutations and autoimmunity. Infection and autoimmunity.
Recognition of alloantibodies. Direct and indirect presentation of alloantibodies. Effector mechanisms of rejection. Hyperacute, acute and chronic rejection. Prevention and treatment of rejection in transplants. xenogeneic transplants.
Topic 6. Modulation of the immune system. Regulation of unwanted immune responses. Immunosuppression. Manipulation of the immune response against infections.

Planning
Methodologies  ::  Tests
  Competences (*) Class hours
 Hours outside the classroom
 (**) Total hours
Introductory activities
1 0 1
Lecture
20 20 40
Seminars
A6
A7
 10 10 20
Presentations / oral communications
A6
A7
 1 8 9
Personal attention
1 0 1
 
Mixed tests
A7
 2 2 4
 
(*) On e-learning, hours of virtual attendance of the teacher.
(**) The information in the planning table is for guidance only and does not take into account the heterogeneity of the students.

Methodologies
Methodologies
  Description
Introductory activities Presentation of the course and the selected syllabus.
Lecture Development of the theoretical syllabus.
Seminars Specific topics on immunological techniques applied to the clinic and biotechnology will be discussed. Advances in the area of immunotherapy will be explained and discussed.
Presentations / oral communications Students must present an immune problem given by the teacher (in the clinical or technological area) and will have to propose a solution to solve it by applying the knowledge acquired.
Personal attention Resolution of doubts related to the subject.

Personalized attention
Description
It is recommended to send an email to the responsible teacher to establish a favorable day and time for both.

Assessment
Methodologies Competences Description Weight        
Lecture
Tests (partial) with questions to develop, and short questions from the agenda developed in the lectures. 60
Seminars
A6
A7
 Short questions about the topics developed. 20
Presentations / oral communications
A6
A7
 Exposition of an immune problem. The student must design a scientifically based strategy for its resolution.. 20
Mixed tests
A7
 Tests (partial) with questions to develop, and short questions from the agenda developed in the lectures.
Others  
 
Other comments and second exam session

  • In order to average the final grade it is essential to pass the partial tests (mixed tests) with a minimum of 4/10 in each partial.
  • In order to pass the subject it will be necessary to obtain a minimum grade of 5/10 once all the partials and evaluable methodologies have been counted.

2nd CALL

FIRST PART: Corresponding to Master Sessions (mixed tests) and Seminars. Objective tests to develop, test questions and/or short questions. The student must obtain at least 40% of the score of this part to be evaluated.

During the evaluation tests, mobile phones, tablets and other devices that are not expressly authorized by the test must be turned off and out of sight. The demonstratively fraudulent realization of any evaluative activity of any subject in both material and virtual and electronic support entails the student the failure mark of this evaluative activity. Regardless of this, given the seriousness of the facts, the center can propose the initiation of a disciplinary file, which will be initiated by resolution of the rector.

Sources of information

Basic J.R. Regueiro, C. López et al., Immunología: Biología y patología del sistema immune, Última edició disponible,
R. Coico, G. Sunshine et al., Immunology a short course, Última edició disponible,
A. K. Abbas, A.W. Lichtman, Inmunologia celular y molecular, Última edició disponible,


Inmunologia celular y molecular. (2008) 6ª ed. A.k. Abbas i A.W. Lichtman. ED. McGraw-Hill – Interamericana

Immunology a short course. (2003) 5ª ed. R. Coico, G. Sunshine i E. Benjamin. ED. Wiley-Liss

Immunología. Biología y patología del sistema immune. (2002) 3ª ed. J.R. Regueiro, C. López et al. ED. Médica Panamericana
Complementary

Recommendations


Subjects that it is recommended to have taken before
MICROBIOLOGY/19204112
IMMUNOLOGY/19204109
(*)The teaching guide is the document in which the URV publishes the information about all its courses. It is a public document and cannot be modified. Only in exceptional cases can it be revised by the competent agent or duly revised so that it is in line with current legislation.