|
Type A
|
Code |
Competences Specific | | | A5 |
Know the principles, the instrumentation and the applications of the main techniques of analysis and separation of biomolecules, as well as the techniques of culture of microorganisms and cells of multicellular organisms. |
| | A10 |
Know how to apply the basic knowledge of structure and function of multicellular organisms in the production of biotechnological products. |
|
Type B
|
Code |
Competences Transversal |
|
Type C
|
Code |
Competences Nuclear |
|
Type A
|
Code |
Learning outcomes |
| | A5 |
It clearly identifies the main limitations and points to consider when designing a possible histological solution to a problem.
| | | A10 |
Clearly identify which are the main limitations and points to take into account to design a possible histological solution to a problem.
|
|
Type B
|
Code |
Learning outcomes |
|
Type C
|
Code |
Learning outcomes |
| Topic |
Sub-topic |
| 1. Introduction to tissue engineering: History, cells and materials used. The challenge of imitating nature: the importance of the cellular microenvironment in functionality. Applications and future perspectives. |
|
| 4. Cell signalling. The basis of cell signalling. Receptors. Intracellular signalling. Protein phosphorilation and other covalent reversible modifications. Scarring process as an example of cell signalling |
|
| 3. Morphogenesis, generation of the tissue in the embryo. Morphogenesis and cell therapy. The desenvolupament of certain systems and organs: Examples: Application of the engineering of tissues in the generation of bone and articulation |
|
| 2. Homeostasis of tissues. Definition of the terms homeostasis, regeneration and tissue repair. Type of fabrics according to their regeneration capacity: Consequences of regeneration capacity in tissue engineering |
|
| 5. The extracellular matrix as a biological support for tissue engineering. Definition, composition and characteristics of the extracellular matrix. Role of the extracellular matrix in biological processes. Biological activity of the supports. future considerations |
|
| 6. Cells sources. Stem cells. Basic concepts about stem cells, type, characteristics, origin and its regulation *. Techniques used for the generation of pluripotent stem cells (cellular reprogramming). Examples: application of stem cells in certain human diseases. |
|
| 7. Biocompatibility. Definition. Evolution and current concept of Biocompatibility. The biocompatibility agents. Biocompatibility in tissue engineering. |
|
| 8 Technologies for tissue fabrication. Scaffold free methods. Scaffold-based systems.Cell and organ printing... |
|
| 9. Biomaterials. Definition. Classification and selsection. Properties. Examples of biolgical origin, synthetic origin and bioceramics |
|
| 10. Bioreactors for tissue engineering. Functions of bioreactors in tissue engineering. Basic principles for the design of bioreactors and development. Type of bioreactors. Bioreactors in clinical applications. Examples. Future perspectives. |
|
| Methodologies :: Tests |
| |
Competences |
(*) Class hours
|
Hours outside the classroom
|
(**) Total hours |
| Introductory activities |
|
0.5 |
0 |
0.5 |
| Lecture |
|
13 |
34 |
47 |
| Presentations / oral communications |
|
10 |
15 |
25 |
| Personal attention |
|
0.5 |
0 |
0.5 |
| |
| Mixed tests |
|
2 |
0 |
2 |
| |
(*) On e-learning, hours of virtual attendance of the teacher.
(**) The information in the planning table is for guidance only and does not take into account the heterogeneity of the students. |
Methodologies
| |
Description |
| Introductory activities |
Subject presentation. |
| Lecture |
Teacher's exposition of the content of the course.
|
| Presentations / oral communications |
Exposition by students (in pairs) of a topic related to the subject selected by them, with the approval of the teacher. |
| Personal attention |
Answer to the queries of the students.
|
|
Description |
|
Resolution of the doubts or queries of the students. It is recommended to previously notify the teacher by email (anna.ardevol@urv.cat). |
|
Methodologies |
Competences
|
Description |
Weight |
|
|
|
|
| Presentations / oral communications |
|
Quality of the material presented
Presentation and defense
It is necessary to attend at least 50% session to obtain this 30% of the final grade
|
20% 10% |
| Mixed tests |
|
All the contents worked on the subject |
60% |
| Others |
|
Participation and quality of the material to the forums proposed in class |
10% |
| |
|
Other comments and second exam session |
|
The evaluation of the quality of the presentation of each tem, will be done by the teacher. The whole presentation (10% of the final grade) will be carried out by the teacher (60%) and classmates (40%). The mixed test must be passed, at 40% of its value, in order to add the value of the presentation/exposition activity and achieve the final grade. In the evaluation of the second call the mark and the weight of the mark of the seminars and the presentation of the assigned work will be maintained. During the evaluation tests, mobile phones, tablets and other devices that are not expressly authorized by the test must be turned off and out of sight. The demonstratively fraudulent realization of any evaluative activity of any subject in both material and virtual and electronic support entails the student the failure mark of this evaluative activity. Regardless of this, given the seriousness of the facts, the center can propose the initiation of a disciplinary file, which will be initiated by resolution of the rector. |
| Basic |
van Blitterswijk, C, Tissue Engineering, New Rochelle, NY : Mary Ann Liebert, Inc , 2008
Lanza, R. Langer R, Vacanti J, , Principles of Tissue Engineering, MA : Elsevier Academic Press, 2007
Ratner, B D et al, Biomaterials Science. An introduction to Materials in Medicine, San Diego : Elsevier, 2004
Lanza, R et al, Essentials of stem cell biology, San Diego, CA ; London, UK : Academic Press, 2009
ALberts, B et al, Molecular Biology of the Cell, New York [etc.] : Garland Science, cop, Darrera edició
, http://www.stembook.org/node/396, ,
Plunkett N, O'Brien FJ, Bioreactors in tissue engineering, , Technol Health Care. 2011;19(1):55-69.
|
|
| Complementary |
|
|
| Subjects that it is recommended to have taken before |
| BIOCHEMISTRY/19204008 | | CELL BIOLOGY/19204006 | | CELL CULTURES/19204115 |
|
(*)The teaching guide is the document in which the URV publishes the information about all its courses. It is a public document and cannot be modified. Only in exceptional cases can it be revised by the competent agent or duly revised so that it is in line with current legislation. |
|