| Educational guide Faculty of Chemistry |
english |
| Synthesis, Catalysis and Molecular Design (2013) |
 Subjects |
| STRUCTURAL DETERMINATION TECHNIQUES |
| Contents |
| IDENTIFYING DATA | 2013_14 |
| Subject | STRUCTURAL DETERMINATION TECHNIQUES | Code | 13685102 | |||||
| Study programme |
|
Cycle | 2nd | |||||
| Descriptors | Credits | Type | Year | Period | ||||
| 6 | Compulsory | First | Only annual |
|||||
| Competences | Learning aims | Contents |
| Planning | Methodologies | Personalized attention |
| Assessment | Sources of information | Recommendations |
| Topic | Sub-topic |
| MASS SPECTROMETRY |
|
| 1. Introduction. Definitions. High resolution, low resolution. | |
| 2. Ionization methods. |
2.1.- Electron Ionization. Fundamentals. Mechanisms, fragmentations. 2.2. Chemical ionization. Fundamentals. Examples. 2.3. FAB, SIMS, MALDI. Fundamentals. Examples. 2.4. Atmospheric Pressure Ionization (API) techniques. ESI and APCI: Fundamentals. Description. |
| 3.- Instrumentation |
3.1.- Analyzers: Quadrupole, Magnetic Sector, Ion Trap, Time of flight (TOF), Fourier Transform Ion Ciclotron Resonance (FT-ICR). 3.1.1.- Mass Spectrometry in tandem: MS/MS, MSn. 3.2.- Detectors: Faraday Cup, Multichannel plate… |
| 4.- Hyphenated Methods: GC-MS, LC-MS |
|
| MAGNETIC NUCLEAR RESONANCE |
|
| 5. Review of fundamental concepts: chemical displacement and coupling constants |
|
| 6. Pulse experiments. | |
| 7. Instrumental aspects. |
|
| 8. Spectral properties: |
- Symmetry and Magnetic Equivalence. - Second Order Effects. - Simulation Programmes. - Exchange Processes. |
9. Spectrum modifications: |
- Displacement reactions. - Spin Decoupling. - The Nuclear Overhauser Effect. |
| 10. Multiple pulse experiments. |
|
| 11. Bidimensional resonance experiments. | |
| 12. Practical exercises. |
