2016_17
Educational guide 
Faculty of Chemistry
A A 
english 
Nutrition and Metabolism (2012)
 Subjects
  CELL SIGNALING
   Contents
Topic Sub-topic
Topic 1. Necessity of cell functions control. Control mechanisms of cell function. Basic principles of cell signalling and basic concepts.
Topic 2. Receptors: Types of receptors. Membrane and nuclear receptors. Overview of cell signalling.
Topic 3. G Proteins. Timeric and monomerica G proteins.
Topic 4. Cyclic nucleotides: cAMP and adenylate cyclase. cGMP and guanylate cyclase. Phospodiesterases.
Topic 5. Inositol phosphate and other membrane lipids: phosphatidylinositols.
Inositol 1,4,5-trisphosphate and diacylglycerols. Other molecules derived of lipids that act as signals.
Topic 6. Calcium: calcium-dependent proteins. Calmodulin. Concentration and intracelular stores of calcium. Mechanisms that mobilize calcium.
Topic 7. Protein kinases and protein phosphatases: serine/threonine kinases. Tyrosine kinases. Mitogen-activated protein kinases. Phosphatases.
Topic 8. Mechanisms of insulin, glucagon, catecholamines and leptin signalling.