2021_22
Educational guide 
Faculty of Chemistry
A A 
english 
Nutrition and Metabolism (2012)
 Subjects
  INSIGHTS IN MOLECULAR NUTRITION
   Contents
Topic Sub-topic
Topic 1. Introduction to Molecular Nutrition Concept of molecular nutrition against the “classic” concept of nutrition. Gene regulation and nutrient-gene interactions. Regulation types for nutrients. Research methods in molecular nutrition: application of genomic and post-genomic technologies. Trends of molecular nutrition: nutrigenomics and nutrigenetics.
Topic 2. Nutrigenomics. Role of nutrients on gene expression Gene regulation by carbohydrates. Nuclear receptors as metabolic sensors. Gene regulation by fats: fatty acids, cholesterol. Gene regulation by amino acids. Gene regulation by vitamins.
Topic 3. Nutrigenetics. Diet and genetic polymorphisms. Genetic differences in the perception of taste. Sensitivity to bitter taste.
Topic 4. Nutrition and epigenetics. Diet and DNA methylation. Niacin status, poly(ADP-ribose) metabolism and genomic instability. Diet and miRNAs.
Topic 5. Nutrigenomics and longevity Processes associated with aging. Theory of aging based on ROS of mitochondrial origin. Effect of caloric restriction and protein restriction on longevity.
Topic 6. Microbiota Microbiota and its immunomodulatory action at
intestinal level