2021_22
Educational guide 
Faculty of Chemistry
A A A 
english 
Nutrition and Metabolism (2012)
 Subjects
  IMMUNONUTRITION
   Contents
Topic Sub-topic
TEMA 1. INTRODUCTION Planning of the subject. Immunonutrition; origin and evolution. Strategies and limitations of immunonutrition studies. Modulation and biomarkers of immune function. Immunonutrition in special situations. Functional foods on the immune system.
TEMA 2. IMMUNE RESPONSE Elements of the immune system. Innate and adaptive immune response. Mucosal defence systems: intestinal microbiota and lymphoid tissue. Immune-based pathologies: inflammation and hypersensitivity.
TEMA 3. FATTY ACIDS AND IMMUNE SYSTEM Structure, source and classification of polyunsaturated fatty acids (PUFAs) with functions of the immune system (-3 y -6). Mechanisms of action and effects of PUFA on the immune system. Experimental and clinical studies on PUFAs and immune function. Role of PUFAs on neonatal immune programming.
TEMA 4. MICRONUTRIENTS WITH ANTIOXIDANT EFFECTS: VITAMINS AND MINERALS Cellular oxidative balance. Oxidative imbalance and immune system. Trace elements with antioxidant/immunomodulatory action: iron, copper, zinc and selenium. Vitamins with antioxidant/immunomodulatory effects: vitamin C, vitamin E, and carotenoids. Multivitaminics.
TEMA 5. POLIFENOLS AND IMMUNE SYSTEM Structure, classification, food sources and bioavailability of polyphenols. Immunomodulatory actions: antioxidant enzyme regulation, capacity to modify the microbiota, modulation of intra and extracelular signaling. Experimental and clinical studies on polyphenols and immune function.
TEMA 6. IMMUNOMODULATORY ACTION OF PROBIOTICS AND PREBIOTICS Probiotics: immunomodulatory effects of acid lactic bacteria. Action mechanisms and immunomodulatory effects of probiotics: in vitro, in vivo and clinical studies.
Probiotics as adyuvant in diseases of immune dysfunction. Prebiotics: classification. Action mechanisms and immunomodulatory effects of prebiotics: in vitro, in vivo and clinical studies. Pro- and prebiotics in the early stages of life; immune programming.
TEMA 7. OTHER NUTRIENTS AND IMMUNE SYSTEM Vitamin A. Vitamin B. Vitamin D. Amino acids. Nucleotides.
TEMA 8. BREAST MILK Breast milk and infant immune system. Anti-infective components: immunoglobulins, lactoferrin, lysozyme, oligosaccharides and fats. Components that promote healthy intestinal microbiota: pro- and prebiotics. Components that promote the development of immune system: leukocytes, cytokines, nucleotides, hormones/bioactive peptides and PUFA. Tolergoenic and anti-inflammatory components: cytokines and PUFA. Human milk banks and infant formulas.